Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29306660 | 0.93 | SPHK1 (0.50) | SPHK1DRD2DRD4EPHX1 | |
| SCHEMBL23133081 | 0.92 | SPHK1 (0.47) | ACHESPHK1CYP3A4CYP2C19EPHX1 | |
| SCHEMBL3427647 | 0.86 | SPHK1 (0.54) | SPHK1CYP3A4CYP2C19EPHX1LMNA | |
| SCHEMBL22549640 | 0.84 | POLB (0.45) | SPHK1DRD2DRD4CYP3A4CYP2C19 | |
| SCHEMBL25632161 | 0.80 | DRD2 (0.42) | SPHK1DRD2DRD4CYP3A4CYP2C19 | |
| SCHEMBL26081876 | 0.79 | ALDH1A1 (0.40) | DRD2DRD4CYP2C19EPHX1LMNA | |
| SCHEMBL23329478 | 0.79 | POLB (0.47) | SPHK1CYP3A4CYP2C19EPHX1LMNA | |
| SCHEMBL2998347 | 0.79 | CYP3A4 (0.43) | ACHESPHK1CYP3A4CYP2C19EPHX1 | |
| SCHEMBL24654083 | 0.79 | DRD2 (0.44) | DRD2DRD4CYP3A4CYP2C19LMNA | |
| SCHEMBL22170861 | 0.79 | PAOX (0.50) | SPHK1DRD2DRD4CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204288-A1 | BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2022-09-29 | — | — | WO | disclosed |