Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.41 |
| ▸ | PPARA | Q07869 | 10/20 | 0.41 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003422 | 1.00 | PPARD (0.41) | PPARDPPARAPPARGRARBTHRA | |
| SCHEMBL30003698 | 0.91 | PPARD (0.43) | PPARDPPARAPPARGMAPTS1PR1 | |
| SCHEMBL24743197 | 0.91 | PPARD (0.43) | PPARDPPARAPPARGMAPTS1PR1 | |
| SCHEMBL12732426 | 0.90 | PPARD (0.44) | PPARDPPARAPPARGRARBTHRA | |
| SCHEMBL2466205 | 0.90 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL2464438 | 0.89 | PPARA (0.43) | PPARDPPARAPPARGRARBTHRA | |
| SCHEMBL24742581 | 0.88 | PPARD (0.54) | PPARDPPARAPPARGMAPT | |
| SCHEMBL30002969 | 0.88 | PPARD (0.54) | PPARDPPARAPPARGMAPT | |
| SCHEMBL24656238 | 0.88 | THRA (0.43) | PPARDPPARAPPARGRARBTHRA | |
| SCHEMBL30003764 | 0.88 | THRA (0.43) | PPARDPPARAPPARGRARBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278952-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2023-09-07 | — | — | US | disclosed |
| US-20230278952-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2023-09-07 | — | — | US | disclosed |
| US-20220363632-A1 | Compounds Useful for Treating Liver Diseases | ABIONYX PHARMA SA (FR) | 2022-11-17 | — | — | US | disclosed |
| WO-2022189856-A9 | COMPOUNDS USEFUL FOR TREATING LIVER DISEASES | ABIONYX PHARMA SA (FR) | 2022-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278952-A1 | Compounds Useful for Treating Liver Diseases | SLC10A1, FABP1, CPT1A | PPARD 332/4885PPARA 94/4885PPARG 71/4885 |
| US-20220363632-A1 | Compounds Useful for Treating Liver Diseases | SLC10A1, FABP1, CPT1A | PPARD 332/4885PPARA 94/4885PPARG 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.