SCHEMBL24656741

SCHEMBL24656741

c1ccc2cc(-c3nc(-c4ccc(-c5ccc(-c6ccc(-c7ccc8ccc(-c9nc(-c%10ccc(-c%11cccc%12ccccc%11%12)cc%10)nc(-c%10cccc%11oc%12ccccc%12c%10%11)n9)cc8c7)cc6)cc5)cc4)nc(-c4cccc5oc6ccccc6c45)n3)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
PIM1 P11309 2/20 0.37
ENPP3 O14638 1/20 0.37
ENPP1 P22413 1/20 0.37
ALDH1A1 P00352 6/20 0.37
MAPT P10636 4/20 0.37
KDM4E B2RXH2 5/20 0.36
HSD17B10 Q99714 5/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
HPGD P15428 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 2/20 0.36
TP53 P04637 2/20 0.36
MAPK1 P28482 2/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23822808 0.96 PIM1 (0.39) CA12CA1CA2CA9PIM1
SCHEMBL26260396 0.95 PIM1 (0.39) CA12CA1CA2CA9PIM1
SCHEMBL23819409 0.94 CA12 (0.38) CA12CA1CA2CA9PIM1
SCHEMBL21148465 0.94 PIM1 (0.38) CA12CA1CA2CA9PIM1
SCHEMBL26260466 0.94 PIM1 (0.39) PIM1ENPP3ENPP1ALDH1A1MAPT
SCHEMBL23822810 0.94 ALDH1A1 (0.38) PIM1ALDH1A1MAPTKDM4EHSD17B10
SCHEMBL21148476 0.94 ALDH1A1 (0.38) PIM1ALDH1A1MAPTKDM4EHSD17B10
SCHEMBL23232321 0.94 ALDH1A1 (0.38) PIM1ALDH1A1MAPTKDM4EHSD17B10
SCHEMBL27118123 0.93 CA12 (0.36) CA12CA1CA2CA9PIM1
SCHEMBL23821525 0.93 PIM1 (0.37) CA12CA1CA2CA9PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243100-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed