SCHEMBL21148465

SCHEMBL21148465

c1ccc2cc(-c3ccc(-c4nc(-c5ccc(-c6cccc7oc8ccccc8c67)cc5)nc(-c5cccc6ccccc56)n4)cc3)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.38
ALDH1A1 P00352 6/20 0.37
KDM4E B2RXH2 5/20 0.37
HSD17B10 Q99714 5/20 0.37
MAPT P10636 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 2/20 0.37
TP53 P04637 2/20 0.37
MAPK1 P28482 2/20 0.37
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26260396 0.96 PIM1 (0.39) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL21149221 0.95 ALDH1A1 (0.39) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL23820721 0.95 BACE1 (0.39) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL26374298 0.95 BACE1 (0.39) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL24656741 0.94 CA12 (0.39) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL21148463 0.94 PIM1 (0.40) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL24888356 0.94 PIM1 (0.40) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL24523465 0.93 ALDH1A1 (0.40) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL24523603 0.93 ALDH1A1 (0.40) PIM1ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL26271134 0.93 ALDH1A1 (0.40) PIM1ALDH1A1KDM4EHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230301189-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-21 US disclosed
US-20230301189-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-21 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PIM1 3381/4885ALDH1A1 191/4885KDM4E 4500/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PIM1 3381/4885ALDH1A1 191/4885KDM4E 4500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.