Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534972 | 0.80 | MAPT (0.58) | ALDH1A1GAAKMT2AMEN1NOX1 | |
| SCHEMBL132620 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA | |
| SCHEMBL3067730 | 0.79 | GAA (0.86) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA | |
| SCHEMBL8956322 | 0.77 | ALDH1A1 (0.94) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA | |
| SCHEMBL9470190 | 0.77 | ALDH1A1 (0.94) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA | |
| SCHEMBL17956747 | 0.76 | KMT2A (0.69) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA | |
| SCHEMBL28438914 | 0.76 | IDO1 (0.62) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL16513250 | 0.76 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA | |
| SCHEMBL1465857 | 0.75 | SMN1; SMN2 (0.64) | ALDH1A1GAAKMT2AMEN1RAB9A | |
| SCHEMBL730314 | 0.75 | ALDH1A1 (0.80) | ALDH1A1CYP3A4TAS2R38HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111410283-A | Agent for removing chloride ions in strongly acidic copper-containing wastewater and method for removing chloride by using same | 中国科学院生态环境研究中心 | 2020-07-14 | — | — | CN | claimed |
| CN-111410283-A | Agent for removing chloride ions in strongly acidic copper-containing wastewater and method for removing chloride by using same | 中国科学院生态环境研究中心 | 2020-07-14 | — | — | CN | disclosed |
| EP-2550266-B1 | HETEROCYCLIC COMPOUNDS USEFUL FOR KINASE INHIBITION | AMITECH THERAPEUTICS SOLUTIONS INC (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9212151-B2 | Heterocyclic compounds useful for kinase inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150158828-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. | 2015-06-11 | — | — | US | disclosed |
| CN-102770479-B | Chloro-substituted polyetherimides having improved relative thermal index | SABIC INNOVATIVE PLASTICS IP | 2014-05-21 | — | — | CN | disclosed |
| EP-2550266-A2 | HETEROCYCLIC COMPOUNDS USEFUL FOR KINASE INHIBITION | Amitech Therapeutics Solutions, Inc. (US) | 2013-01-30 | — | — | EP | disclosed |
| CN-102770479-A | Chloro-substituted polyetherimides having improved relative thermal index | SABIC INNOVATIVE PLASTICS IP | 2012-11-07 | — | — | CN | disclosed |
| WO-2011119894-A2 | HETEROCYCLIC COMPOUNDS USEFUL FOR KINASE INHIBITION | KINAGEN, INC (US) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158828-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | MAP4K2, MAP3K20, MAP3K19 | ALDH1A1 3693/4885CYP3A4 4260/4885TAS2R38 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.