⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357780 | 1.00 | — | — | |
| SCHEMBL29488972 | 1.00 | — | — | |
| Acetone SCHEMBL28220172 | 0.87 | KDM4E (0.50) | — | |
| SCHEMBL27440988 | 0.77 | RAB9A (0.50) | — | |
| SCHEMBL27996985 | 0.72 | EGFR (0.52) | — | |
| SCHEMBL43935 | 0.72 | — | — | |
| SCHEMBL29463643 | 0.72 | — | — | |
| SCHEMBL4614 | 0.72 | — | — | |
| SCHEMBL30935767 | 0.72 | DYRK1A (0.63) | — | |
| SCHEMBL29370280 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2367 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241425-A | Preparation method of 2-amino-4-bromopyridine | 上海若济生物医药科技有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118878516-A | Pyrophosphate indicator and preparation method and application thereof | 南昌大学 | 2024-11-01 | — | — | CN | claimed |
| CN-117402289-A | Room-temperature phosphorescent material of polyacrylamide copolymer containing biaryl compound and preparation method thereof | 广东工业大学 | 2024-01-16 | — | — | CN | claimed |
| CN-115160310-B | Alternanthene derivatives as CDK2/Topo I inhibitors, preparation method thereof and antitumor application thereof | 中国人民解放军北部战区总医院 | 2023-06-23 | — | — | CN | claimed |
| CN-115160298-B | Tacrine-sulfonamide derivative and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2023-05-23 | — | — | CN | claimed |
| CN-114432900-B | Preparation method of anti-pollution composite reverse osmosis membrane and anti-pollution composite reverse osmosis membrane prepared by same | 沃顿科技股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115160298-A | Tacrine-sulfonamide derivative and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2022-10-11 | — | — | CN | claimed |
| CN-115160310-A | Sinomenine derivatives as CDK2/Topo I inhibitor, and preparation method and anti-tumor application thereof | 中国人民解放军北部战区总医院 | 2022-10-11 | — | — | CN | claimed |
| CN-114890955-A | Preparation process of N-substituted morpholine organic compound | 江西瑞威尔生物科技有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-114432900-A | Preparation method of anti-pollution composite reverse osmosis membrane and anti-pollution composite reverse osmosis membrane prepared by same | 沃顿科技股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-108752270-A | A kind of 4- bromo-2-pyridyl amides compounds of the ether structure containing hexichol | 湖南博隽生物医药有限公司 | 2018-11-06 | — | — | CN | claimed |
| US-20180141940-A1 | SALT FORM AND CRYSTAL FORM OF 1,2,5-THIADIAZOLIDIN-1,1-DIOXIDE, PREPARATION METHOD THEREOF AND INTERMEDIATE | JIANGSU KANION PARMACEUTICAL CO. LTD (CN) | 2018-05-24 | — | — | US | claimed |
| CN-105153023-B | The synthetic method of 2 amino, 4 bromopyridine | 成都同创源医药科技有限公司 | 2018-04-13 | — | — | CN | claimed |
| EP-3257851-A1 | SALT FORM AND CRYSTAL FORM OF 1,2,5 THIADIAZOLIDIN-1,1-DIOXIDE, PREPARATION METHOD THEREOF AND INTERMEDIATE | Jiangsu Kanion Pharmaceutical Co., Ltd. (CN) | 2017-12-20 | — | — | EP | claimed |
| CN-107406439-A | Salt form and crystal form of 1,2, 5-thiadiazolidine-1, 1-dioxide, preparation method and intermediate thereof | 江苏康缘药业股份有限公司 | 2017-11-28 | — | — | CN | claimed |
| CN-104744433-B | ALD and the purposes as EV71 virus with CAV16 viral inhibitors thereof | 中国科学院生物物理研究所 | 2016-09-21 | — | — | CN | claimed |
| CN-105153023-A | Synthetic method of 2-amino-4-bromopyridine | CHENGDU TONGCHUANGYUAN PHARMACEUTICAL CO LTD | 2015-12-16 | — | — | CN | claimed |
| CN-104744433-A | ALD and application thereof as EV71 virus and CAV16 virus inhibitor | INST BIOPHYSICS CN ACAD SCI | 2015-07-01 | — | — | CN | claimed |
| CN-103772271-A | Novel synthetic method for 2-amino-4-bromopyridine | CHENGDU KAIXIN TIANRUI TECHNOLOGY DEV CO LTD | 2014-05-07 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |