SCHEMBL24659270

SCHEMBL24659270

C=C(C)C(=O)OCCCN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HDAC3 O15379 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
NCOR2 Q9Y618 2/20 0.47
MAOB P27338 5/20 0.46
TSHR P16473 3/20 0.45
SCN1A P35498 2/20 0.44
SCN2A Q99250 2/20 0.44
SCN3A Q9NY46 2/20 0.44
BCHE P06276 2/20 0.43
ACHE P22303 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM1 P11229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11314572 0.93 MAOB (0.55) MAOBSCN1ASCN2ASCN3ABCHE
SCHEMBL7202690 0.91 TSHR (0.53) POLBAPEX1HTTTDP1HDAC3
Hydrochloric Acid SCHEMBL28088429 0.86 SMN1; SMN2 (0.56) BCHEACHESMN1; SMN2
SCHEMBL23694604 0.85 TDP1 (0.49) POLBAPEX1HTTTDP1HDAC3
SCHEMBL30751954 0.84 MAOB (0.52) POLBMAOBTSHRSCN1ASCN2A
SCHEMBL27726006 0.83 TSHR (0.46) MAOBTSHRSCN1ASCN2ASCN3A
SCHEMBL15628019 0.82 MEN1 (0.54) POLBAPEX1HTTTDP1TSHR
SCHEMBL13042240 0.82 ALDH1A1 (0.43) POLBAPEX1HTTTDP1TSHR
SCHEMBL8399549 0.82 HDAC3 (0.54) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL24279649 0.81 SMN1; SMN2 (0.63) POLBTDP1TSHRACHESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116639782-A Wet type coating room circulating water treatment agent, method for capturing paint and water treatment method 栗田工业(大连)有限公司 2023-08-25 CN disclosed
US-11622916-B2 Photocurable composition excellent in curing depth SHOFU INC. (JP) 2023-04-11 US disclosed
US-20220401312-A1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY SHOFU INC. (JP) 2022-12-22 US disclosed
US-20220387263-A1 DENTAL PHOTOCURABLE COMPOSITION HAVING EXCELLENT STORAGE STABILITY SHOFU INC. (JP) 2022-12-08 US disclosed
EP-4062894-A1 DENTAL PHOTOCURABLE COMPOSITION HAVING EXCELLENT STORAGE STABILITY Shofu Inc. (JP) 2022-09-28 EP disclosed
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH SHOFU INC. (JP) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11622916-B2 Photocurable composition excellent in curing depth ODC1, AOC2, CCNT1 POLB 226/4885APEX1 239/4885HTT 2687/4885
US-20220287919-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH ODC1, AOC2, CCNT1 POLB 224/4885APEX1 246/4885HTT 2734/4885
US-20220401312-A1 DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY H1-0, CCND1, CCNT1 POLB 769/4885APEX1 161/4885HTT 927/4885
US-20220387263-A1 DENTAL PHOTOCURABLE COMPOSITION HAVING EXCELLENT STORAGE STABILITY H1-0, H1-2, H1-4 POLB 258/4885APEX1 227/4885HTT 1723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.