Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034274 | 0.79 | IDO1 (0.45) | CETPJAK2JAK3PTK2GPR119 | |
| SCHEMBL24659848 | 0.78 | KDM1A (0.58) | KDM1A | |
| SCHEMBL16808834 | 0.76 | KDM1A (0.54) | CETPJAK2JAK3PTK2GPR119 | |
| SCHEMBL30034262 | 0.75 | KDM1A (0.47) | CETPJAK2JAK3PTK2GPR119 | |
| SCHEMBL16797361 | 0.75 | KDM1A (0.69) | CETPJAK2JAK3PTK2GPR119 | |
| SCHEMBL31716198 | 0.75 | TGFBR1 (0.51) | CETPGPR119BRD4IDO1TDO2 | |
| SCHEMBL16797291 | 0.75 | KDM1A (0.58) | CETPJAK2JAK3PTK2GPR119 | |
| SCHEMBL24659676 | 0.74 | KDM1A (0.46) | CETPJAK2JAK3PTK2GPR119 | |
| SCHEMBL17694898 | 0.74 | KDM1A (0.46) | CETPJAK2JAK3PTK2GPR119 | |
| SCHEMBL17694899 | 0.74 | KDM1A (0.46) | CETPJAK2JAK3PTK2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080100-B1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2022-11-30 | — | — | EP | disclosed |