Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 9/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16797382 | 0.89 | KDM1A (0.49) | KDM1A | |
| SCHEMBL24659688 | 0.88 | KDM1A (0.56) | IDO1TDO2KDM1AJAK2JAK3 | |
| SCHEMBL16808849 | 0.88 | KDM1A (0.56) | IDO1TDO2KDM1AJAK2JAK3 | |
| SCHEMBL30034262 | 0.86 | KDM1A (0.47) | KDM1AJAK2JAK3PTK2EGLN2 | |
| SCHEMBL16797266 | 0.83 | KDM1A (0.55) | IDO1TDO2KDM1AEGLN2IRAK1 | |
| SCHEMBL16797291 | 0.83 | KDM1A (0.58) | KDM1AJAK2JAK3PTK2EGLN2 | |
| SCHEMBL17427358 | 0.80 | KDM1A (0.52) | KDM1AEGLN2CETPGPR119 | |
| SCHEMBL24659828 | 0.79 | CETP (0.45) | IDO1TDO2KDM1AJAK2JAK3 | |
| SCHEMBL20753255 | 0.79 | GPR119 (0.43) | KDM1AJAK2JAK3PTK2EGLN2 | |
| SCHEMBL17559028 | 0.78 | KDM1A (0.53) | KDM1AJAK2JAK3PTK2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257591-A2 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | Celgene Quanticel Research, Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-3080100-B1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2022-11-30 | — | — | EP | disclosed |
| EP-3189038-B1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | CELGENE QUANTICEL RES INC (US) | 2022-11-23 | — | — | EP | disclosed |