Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725818 | 0.79 | HTR6 (0.65) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL724590 | 0.73 | HTR6 (0.71) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL29743955 | 0.73 | HTR6 (0.84) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL2464508 | 0.72 | HTR6 (0.56) | HTR6L3MBTL1CYP3A4DRD2HTR2A | |
| SCHEMBL426117 | 0.72 | HTR6 (0.68) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL4941443 | 0.71 | HTR6 (0.80) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL29564964 | 0.70 | HTR6 (0.65) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL28745820 | 0.70 | HTR6 (0.65) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL9095357 | 0.70 | HTR6 (0.65) | HTR6POLBL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL428128 | 0.69 | HTR6 (0.68) | HTR6POLBL3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542081-A1 | COMPOUNDS FOR TREATMENT OF CANCER | Gtx, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109059-A1 | COMPOUNDS FOR TREATMENT OF CANCER | GTX, INC. (US) | 2011-09-09 | — | — | WO | disclosed |