Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457681 | 1.00 | MAPK14 (0.40) | MAPK14PKMSMN1; SMN2NPSR1NPC1 | |
| SCHEMBL30388086 | 0.82 | SMN1; SMN2 (0.40) | PKMSMN1; SMN2NPSR1NPC1RAB9A | |
| SCHEMBL25180336 | 0.82 | SMN1; SMN2 (0.40) | PKMSMN1; SMN2NPSR1NPC1RAB9A | |
| SCHEMBL24661382 | 0.77 | HPD (0.32) | PKMSMN1; SMN2NPSR1HPD | |
| SCHEMBL29457680 | 0.76 | MEN1 (0.33) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL22031793 | 0.76 | MEN1 (0.33) | SMN1; SMN2L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL22031802 | 0.76 | KMT2A (0.36) | SMN1; SMN2NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL29457662 | 0.76 | KMT2A (0.36) | SMN1; SMN2NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL24661318 | 0.75 | POLB (0.34) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28443368 | 0.72 | KMT2A (0.34) | L3MBTL1MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281837-A1 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281837-A1 | SUBSTITUTED PYRIDAZINONES AS HERBICIDES | PDXK, HPD, DDT | MAPK14 1428/4885PKM 231/4885SMN1; SMN2 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.