Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940818 | 0.82 | RXFP1 (0.45) | RXFP1ALDH1A1ACSS2L3MBTL1SYK | |
| SCHEMBL29626649 | 0.82 | RXFP1 (0.45) | RXFP1ALDH1A1ACSS2L3MBTL1SYK | |
| SCHEMBL22944950 | 0.79 | CBLB (0.52) | RXFP1ACSS2SYKCYP17A1RORC | |
| SCHEMBL29640156 | 0.79 | CBLB (0.52) | RXFP1ACSS2SYKCYP17A1RORC | |
| SCHEMBL1013325 | 0.72 | RXFP1 (0.73) | RXFP1LMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30042580 | 0.72 | RXFP1 (0.73) | RXFP1LMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29626593 | 0.71 | RXFP1 (0.52) | RXFP1LMNAALDH1A1ACSS2L3MBTL1 | |
| SCHEMBL31091996 | 0.71 | RXFP1 (0.52) | RXFP1LMNAALDH1A1ACSS2L3MBTL1 | |
| SCHEMBL22944961 | 0.70 | CBLB (0.62) | RXFP1ACSS2RORC | |
| SCHEMBL29640139 | 0.70 | CBLB (0.62) | RXFP1ACSS2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221704-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |