Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 10/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22944950 | 1.00 | CBLB (0.52) | CBLBRXFP1ACSS2SYKRORC | |
| SCHEMBL22944961 | 0.91 | CBLB (0.62) | CBLBRXFP1ACSS2RORCAKR1C3 | |
| SCHEMBL29640139 | 0.91 | CBLB (0.62) | CBLBRXFP1ACSS2RORCAKR1C3 | |
| SCHEMBL21201152 | 0.87 | CBLB (0.55) | CBLBACSS2AKR1C3CYP3A4CYP2C19 | |
| SCHEMBL29626649 | 0.83 | RXFP1 (0.45) | CBLBRXFP1ACSS2SYKRORC | |
| SCHEMBL28940818 | 0.83 | RXFP1 (0.45) | CBLBRXFP1ACSS2SYKRORC | |
| SCHEMBL24660946 | 0.79 | RXFP1 (0.46) | RXFP1ACSS2SYKRORCCYP17A1 | |
| SCHEMBL29866714 | 0.78 | HCRTR1 (0.44) | CBLBRXFP1SYKRORCBRD4 | |
| SCHEMBL21200198 | 0.78 | CBLB (0.66) | CBLBAKR1C3 | |
| SCHEMBL28741753 | 0.76 | CBLB (0.50) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450271-B | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114450271-A | Ureas, amino and substituted heteroaryl compounds for Cbl-b inhibition | 纽力克斯治疗公司 | 2022-05-06 | — | — | CN | disclosed |