Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.43 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335590 | 0.85 | ENPP2 (0.51) | MAPTNPC1HTTENPP2SENP2 | |
| SCHEMBL4335578 | 0.85 | ENPP2 (0.51) | MAPTNPC1HTTENPP2SENP2 | |
| SCHEMBL13599497 | 0.83 | ENPP2 (0.53) | MAPTNPC1HTTENPP2SENP2 | |
| SCHEMBL10535182 | 0.76 | NPC1 (0.44) | MAPTNPC1ENPP2HDAC3HDAC1 | |
| SCHEMBL13880623 | 0.75 | ENPP2 (0.49) | MAPTNPC1HTTENPP2SENP2 | |
| SCHEMBL13793399 | 0.75 | ENPP2 (0.49) | MAPTNPC1HTTENPP2SENP2 | |
| SCHEMBL11425279 | 0.74 | ALDH1A1 (0.44) | MAPTNPC1ENPP2SENP2SENP1 | |
| SCHEMBL8019428 | 0.74 | CYP3A4 (0.46) | MAPTNPC1HTTENPP2HDAC3 | |
| SCHEMBL1939964 | 0.73 | NPC1 (0.44) | MAPTNPC1ENPP2HDAC3HDAC1 | |
| SCHEMBL5888425 | 0.73 | GAA (0.59) | MAPTNPC1SENP2SENP1SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079805-B1 | MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS | BASF SE (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-8013045-B2 | Monoazo colorants for mass-colouring of polymers | BASF SE Ludwigshafen (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20100305247-A1 | MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS | CIBA CORP. | 2010-12-02 | — | — | US | disclosed |
| US-20100168291-A1 | MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS | CIBA CORPORATION (US) | 2010-07-01 | — | — | US | disclosed |
| EP-2079805-A1 | MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS | Ciba Holding Inc. (CH) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008049744-A1 | MONOAZO COLORANTS FOR MASS-COLOURING OF POLYMERS | CIBA HOLDING INC. (CH) | 2008-05-02 | — | — | WO | disclosed |