Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569109 | 0.82 | PLD1 (0.50) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| SCHEMBL1437298 | 0.82 | PLD1 (0.50) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| Ammonia Solution, Strong SCHEMBL28277848 | 0.80 | PLD1 (0.48) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| SCHEMBL31748642 | 0.73 | RPS6KA5 (0.41) | CLK4COMT | |
| SCHEMBL718706 | 0.72 | SMN1; SMN2 (0.62) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| SCHEMBL5100117 | 0.72 | GRM5 (0.47) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| SCHEMBL28379997 | 0.71 | SMN1; SMN2 (0.55) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| SCHEMBL11117869 | 0.71 | POLB (0.47) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| SCHEMBL29760726 | 0.71 | SMN1; SMN2 (0.60) | SMN1; SMN2EP300KAT2BPLD1GAA | |
| SCHEMBL29401947 | 0.71 | CYP3A4 (0.55) | KDM4EALDH1A1MAPK1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698131-A | Pool construction method for water supply of water tower | 中地国际工程有限公司 | 2020-01-17 | — | — | CN | claimed |
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-110698131-A | Pool construction method for water supply of water tower | 中地国际工程有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-110698131-A | Pool construction method for water supply of water tower | 中地国际工程有限公司 | 2020-01-17 | — | — | CN | disclosed |
| EP-2542076-A1 | INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | Merck Sharp & Dohme Corp. (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109254-A1 | INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS | MERCK SHARP & DOHME CORP. (US) | 2011-09-09 | — | — | WO | disclosed |
| CN-101018796-A | Metal complex, light-emitting solid, organic EL element, and organic EL display | FUJI FILM CORP (JP) | 2007-08-15 | — | — | CN | disclosed |
| US-4976774-A | Electromic displays, indicators | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1990-12-11 | — | — | US | disclosed |
| US-4976774-A | Electromic displays, indicators | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 1990-12-11 | — | — | US | disclosed |