SCHEMBL718706

SCHEMBL718706

O=C1C=CC(=O)N1c1ccccn1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.62
KDM4E B2RXH2 3/20 0.53
GAA P10253 2/20 0.53
ALDH1A1 P00352 2/20 0.53
POLB P06746 3/20 0.50
EP300 Q09472 1/20 0.48
KAT2B Q92831 1/20 0.48
TLR9 Q9NR96 1/20 0.48
MGLL Q99685 1/20 0.46
MAPK1 P28482 1/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
HPGD P15428 2/20 0.44
NPC1 O15118 1/20 0.44
S1PR4 O95977 1/20 0.44
XBP1 P17861 1/20 0.44
S1PR1 P21453 1/20 0.44
CCR6 P51684 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29760726 0.98 SMN1; SMN2 (0.60) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL7479419 0.78 ALDH1A1 (0.73) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL30817653 0.78 ALDH1A1 (0.73) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL30817652 0.78 ALDH1A1 (0.73) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL10999884 0.77 SMN1; SMN2 (1.00) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL9788869 0.77 SMN1; SMN2 (0.60) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL28009909 0.75 SMN1; SMN2 (0.48) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL14357435 0.75 KDM4E (0.74) SMN1; SMN2KDM4EGAAALDH1A1POLB
SCHEMBL349418 0.75 MGLL (0.50) ALDH1A1TLR9MGLLBCHEHTT
SCHEMBL30566302 0.74 SMN1; SMN2 (0.61) SMN1; SMN2KDM4EGAAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431678-A Flame retardant composition 长春人造树脂厂股份有限公司 2025-02-14 CN claimed
EP-0202498-B1 USE OF A THERMO-SETTING, POLYMERIZABLE COMPOSITION AND WIRING BOARD HITACHI, LTD. (JP) 1990-07-11 EP claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP claimed
CN-120025660-A Resin composition and use thereof 台燿科技股份有限公司 2025-05-23 CN disclosed
CN-119431678-A Flame retardant composition 长春人造树脂厂股份有限公司 2025-02-14 CN disclosed
CN-118786161-A Copolymers derived from dicyclopentadiene 高新特殊工程塑料全球技术有限公司 2024-10-15 CN disclosed
CN-115038736-B Functionalized poly (arylene ether) copolymers, methods of making, and articles derived therefrom 高新特殊工程塑料全球技术有限公司 2024-06-04 CN disclosed
CN-115335431-B Modified poly (phenylene ether) copolymers, compositions and methods 高新特殊工程塑料全球技术有限公司 2024-05-24 CN disclosed
CN-111004385-B Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-04-12 CN disclosed
CN-117659387-A Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-03-08 CN disclosed
CN-113667232-B Resin composition, prepreg, metal foil laminate and printed wiring board each produced using the same 台燿科技股份有限公司 2023-09-01 CN disclosed
EP-0269021-A1 Resin composition for printed circuit board and such board formed by use thereof HITACHI, LTD. (JP) 1988-06-01 EP disclosed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US disclosed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP disclosed
EP-0078039-B1 THERMOSETTING RESIN COMPOSITION, PREPOLYMER THEREOF AND CURED ARTICLE THEREOF Hitachi, Ltd. (JP) 1986-01-22 EP disclosed
US-4546168-A POLYMERIZABLE EPOXY COMPOUNDS, PHENOLIC COMPOUNDS, AND TRIALLYL ISOCYANURATE COMPOUNDS HITACHI, LTD. (JP) 1985-10-08 US disclosed
US-4482703-A Thermosetting resin composition comprising dicyanamide and polyvalent imide HITACHI, LTD. (JP) 1984-11-13 US disclosed
EP-0123262-A2 Resin encapsulated semiconductor device and process for producing the same HITACHI, LTD. (JP) 1984-10-31 EP disclosed
US-4400438-A MALEIMIDE RESING AND HALOGENATED DIPHENYL ETHER HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-08-23 US disclosed
EP-0078039-A1 Thermosetting resin composition, prepolymer thereof and cured article thereof Hitachi, Ltd. (JP) 1983-05-04 EP disclosed