Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437298 | 0.78 | PLD1 (0.50) | POLBSMN1; SMN2ALDH1A1HTTHSD17B10 | |
| SCHEMBL30569109 | 0.78 | PLD1 (0.50) | POLBSMN1; SMN2ALDH1A1HTTHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28277848 | 0.76 | PLD1 (0.48) | POLBSMN1; SMN2ALDH1A1HTTHSD17B10 | |
| SCHEMBL29401947 | 0.76 | CYP3A4 (0.55) | ALDH1A1HSD17B10TDP1KDM4ELMNA | |
| SCHEMBL117382 | 0.76 | CYP3A4 (0.55) | ALDH1A1HSD17B10TDP1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6446846 | 0.74 | CYP3A4 (0.53) | ALDH1A1HSD17B10TDP1KDM4ELMNA | |
| SCHEMBL1901909 | 0.74 | POLB (0.42) | POLBSMN1; SMN2ALDH1A1HTTHSD17B10 | |
| SCHEMBL31095576 | 0.73 | NOS3 (0.45) | POLBSMN1; SMN2ALDH1A1HTTHSD17B10 | |
| SCHEMBL30337851 | 0.73 | SMN1; SMN2 (0.43) | POLBSMN1; SMN2ALDH1A1HTTHSD17B10 | |
| SCHEMBL22199029 | 0.73 | EGLN2 (0.60) | POLBSMN1; SMN2ALDH1A1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926886-A | Triazole Fe(II) magnetic complex with dimensional plane porous frame structure, and synthesis method and application thereof | UNIV TIANJIN NORMAL | 2015-09-23 | — | — | CN | claimed |
| CN-104761590-A | A triazole Fe (II) magnetic complex having a one-dimensional double-chain frame structure, a high-temperature synthesis method thereof and applications of the complex | UNIV TIANJIN NORMAL | 2015-07-08 | — | — | CN | claimed |
| CN-106170486-B | Novel indazolecarboxamides, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-106488912-A | Inhibitors of renal outer medullary potassium channels | 默沙东公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106170486-A | Novel indazolecarboxamides, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-104926886-A | Triazole Fe(II) magnetic complex with dimensional plane porous frame structure, and synthesis method and application thereof | UNIV TIANJIN NORMAL | 2015-09-23 | — | — | CN | disclosed |
| CN-104761590-A | A triazole Fe (II) magnetic complex having a one-dimensional double-chain frame structure, a high-temperature synthesis method thereof and applications of the complex | UNIV TIANJIN NORMAL | 2015-07-08 | — | — | CN | disclosed |
| CN-102190686-B | Binuclear Fe(II) complex of 4-(2-pyridin-)-1,2,4-triazol and application thereof | UNIV TIANJIN NORMAL | 2013-12-11 | — | — | CN | disclosed |
| CN-102190686-A | Binuclear Fe(II) complex of 4-(2-pyridin-)-1,2,4-triazol and application thereof | UNIV TIANJIN NORMAL | 2011-09-21 | — | — | CN | disclosed |
| WO-2011035064-A2 | TRIAZOLE CATALYSTS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2011-03-24 | — | — | WO | disclosed |
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |