Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467686 | 0.90 | PPARG (0.40) | PPARDPPARGPPARAS1PR1PTGDR2 | |
| SCHEMBL2466103 | 0.90 | PPARD (0.41) | PPARDPPARGPPARAS1PR1PTGDR2 | |
| SCHEMBL1766000 | 0.88 | PPARD (0.40) | PPARDPPARGPPARAS1PR1PTGDR2 | |
| SCHEMBL2466344 | 0.86 | PPARD (0.51) | PPARDPPARGPPARA | |
| SCHEMBL2463460 | 0.83 | PPARD (0.53) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL2464421 | 0.83 | PPARD (0.45) | PPARDPPARGPPARAS1PR1PTGDR2 | |
| SCHEMBL2465182 | 0.82 | PPARD (0.47) | PPARDPPARGPPARAS1PR1PTGDR2 | |
| SCHEMBL2467481 | 0.80 | PPARD (0.38) | PPARDPPARGPPARAS1PR1CTSA | |
| SCHEMBL2466122 | 0.80 | PPARD (0.45) | PPARDPPARGPPARA | |
| SCHEMBL2464201 | 0.79 | PPARD (0.49) | PPARDPPARGPPARACTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |