Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 10/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2463460 | 0.92 | PPARD (0.53) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL2465180 | 0.86 | PPARD (0.61) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL2465204 | 0.86 | PPARD (0.46) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL2463150 | 0.85 | PPARD (0.45) | PPARDPPARGPPARAPTGDR2WNT3A | |
| SCHEMBL4754172 | 0.85 | CRHR1 (0.34) | PPARDPPARGPPARAS1PR1CTSA | |
| SCHEMBL2466103 | 0.83 | PPARD (0.41) | PPARDPPARGPPARAPTGDR2S1PR1 | |
| SCHEMBL2468100 | 0.82 | PPARA (0.37) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL2467686 | 0.82 | PPARG (0.40) | PPARDPPARGPPARAPTGDR2S1PR1 | |
| SCHEMBL2466352 | 0.82 | PPARD (0.40) | PPARDPPARGPPARAPTGDR2S1PR1 | |
| SCHEMBL2464421 | 0.81 | PPARD (0.45) | PPARDPPARGPPARAPTGDR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424330-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2011-09-28 | — | — | EP | disclosed |