Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25473619 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL24780846 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL23886618 | 0.78 | AKR1C1 (0.58) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL25153965 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL22550096 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL24780844 | 0.72 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL1627580 | 0.71 | AKR1C1 (0.68) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL27158792 | 0.69 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL2703559 | 0.68 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNACYP2C19NPSR1 | |
| SCHEMBL24663627 | 0.68 | ALDH1A1 (0.66) | ALDH1A1TSHRLMNACYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | C4 THERAPEUTICS, INC. (US) | 2022-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | CRBN, IKZF1, IKZF3 | ALDH1A1 3827/4885TSHR 3284/4885LMNA 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.