Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24780846 | 0.89 | ALDH1A1 (0.55) | ALDH1A1CYP2C19NPC1MAPTCYP2C9 | |
| SCHEMBL25473619 | 0.89 | ALDH1A1 (0.55) | ALDH1A1CYP2C19NPC1MAPTCYP2C9 | |
| SCHEMBL890180 | 0.86 | AKR1C1 (0.57) | ALDH1A1LMNAAKR1C1OPRD1 | |
| SCHEMBL1627580 | 0.85 | AKR1C1 (0.68) | ALDH1A1CYP2C19NPC1MAPTCYP2C9 | |
| SCHEMBL12928712 | 0.82 | AKR1C1 (0.64) | ALDH1A1LMNANPSR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3737199 | 0.82 | AKR1C1 (0.70) | ALDH1A1LMNANPSR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9137176 | 0.82 | ALOX5 (0.47) | ALDH1A1CYP2C19NPC1MAPTCYP2C9 | |
| SCHEMBL2703559 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP2C19NPC1MAPTCYP2C9 | |
| SCHEMBL24663621 | 0.81 | AKR1C1 (0.52) | ALDH1A1CYP2C19NPC1MAPTCYP2C9 | |
| SCHEMBL1838291 | 0.81 | AKR1C1 (0.68) | LMNANPSR1SMN1; SMN2L3MBTL1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083295-A1 | ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF | SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |
| WO-2022262845-A1 | ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF | SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |