SCHEMBL9684668

SCHEMBL9684668

NC(CC(=O)NO)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.48
GRIK1 P39086 5/20 0.48
GRIK2 Q13002 3/20 0.48
GRM1 Q13255 2/20 0.48
GRM2 Q14416 2/20 0.48
SLC1A1 P43005 6/20 0.46
SLC1A3 P43003 5/20 0.46
SLC1A2 P43004 5/20 0.46
GRIA4 P48058 2/20 0.46
GRIK3 Q13003 2/20 0.46
GRIK5 Q16478 2/20 0.46
SLC7A5 Q01650 1/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GSR P00390 1/20 0.46
CYP1A2 P05177 1/20 0.46
GRM5 P41594 1/20 0.46
GRIA1 P42261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10596071 1.00 FOLH1 (0.48) FOLH1GRIK1GRIK2GRM1GRM2
SCHEMBL11439151 0.82 SLC7A5 (0.45) FOLH1GRIK1GRIK2GRM1GRM2
SCHEMBL12906559 0.80 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC1A1
SCHEMBL24667461 0.80 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC1A1
SCHEMBL14558858 0.79 GRIK1 (0.43) GRIK1GRIK2GRM1GRM2SLC1A1
SCHEMBL3875073 0.78 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2SLC1A1
SCHEMBL8368782 0.78 SLC7A5 (0.50) GRIK1GRIK2GRM1GRM2SLC1A1
SCHEMBL359673 0.78 SLC7A5 (0.50) GRIK1GRIK2GRM1GRM2SLC1A1
SCHEMBL13498370 0.78 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2SLC1A1
SCHEMBL515168 0.78 SLC7A5 (0.50) GRIK1GRIK2GRM1GRM2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-5096700-A Bactericides for dentifrices THE PROCTER & GAMBLE COMPANY (US) 1992-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP FOLH1 6/4885GRIK1 2914/4885GRIK2 3197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.