⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344726 | 0.94 | KMT2A (0.38) | — | |
| SCHEMBL4421224 | 0.78 | — | — | |
| SCHEMBL5151268 | 0.78 | — | — | |
| SCHEMBL9353783 | 0.73 | PSEN1 (0.30) | — | |
| SCHEMBL9353778 | 0.73 | PSEN1 (0.30) | — | |
| SCHEMBL2350488 | 0.72 | L3MBTL1 (0.44) | — | |
| SCHEMBL6960442 | 0.71 | — | — | |
| SCHEMBL6240475 | 0.70 | — | — | |
| SCHEMBL2346034 | 0.69 | AKR1C3 (0.35) | — | |
| SCHEMBL294017 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12478620-B2 | Cyano-substituted cyclic hydrazine derivative and application thereof | E-NITIATE BIOPHARMACEUTICALS (HANGZHOU) CO., LTD (CN) | 2025-11-25 | — | — | US | disclosed |
| US-20220339146-A1 | CYANO-SUBSTITUTED CYCLIC HYDRAZINE DERIVATIVE AND APPLICATION THEREOF | E-NITIATE BIOPHARMACEUTICALS (HANGZHOU) CO., LTD (CN) | 2022-10-27 | — | — | US | disclosed |
| US-20220339146-A1 | CYANO-SUBSTITUTED CYCLIC HYDRAZINE DERIVATIVE AND APPLICATION THEREOF | E-NITIATE BIOPHARMACEUTICALS (HANGZHOU) CO., LTD (CN) | 2022-10-27 | — | — | US | disclosed |
| EP-4032888-A1 | CYANO-SUBSTITUTED CYCLIC HYDRAZINE DERIVATIVE AND APPLICATION THEREOF | E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd (CN) | 2022-07-27 | — | — | EP | disclosed |