Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353778 | 1.00 | PSEN1 (0.30) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8944083 | 0.77 | S1PR1 (0.41) | — | |
| SCHEMBL24667751 | 0.73 | — | — | |
| SCHEMBL2344726 | 0.71 | KMT2A (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15445233 | 0.69 | SLC18A2 (0.42) | KMT2A | |
| SCHEMBL8944270 | 0.67 | ACHE (0.42) | KMT2A | |
| SCHEMBL8944266 | 0.67 | ACHE (0.42) | KMT2A | |
| SCHEMBL12188670 | 0.67 | KMT2A (0.32) | KMT2A | |
| SCHEMBL25019594 | 0.67 | KMT2A (0.36) | KMT2A | |
| SCHEMBL16735694 | 0.66 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613474-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993010109-A1 | METHOD OF PREPARING 1-AMINO-2,6-DIMETHYLPIPERIDINE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-05-27 | — | — | WO | disclosed |