Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 17/20 | 0.33 |
| ▸ | CA1 | P00915 | 7/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.31 |
| ▸ | CA5A | P35218 | 4/20 | 0.31 |
| ▸ | CA7 | P43166 | 4/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.31 |
| ▸ | CA4 | P22748 | 3/20 | 0.31 |
| ▸ | CA6 | P23280 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24668632 | 0.95 | CA2 (0.33) | LOXLOXL2PDPK1CA2CA1 | |
| SCHEMBL24668662 | 0.83 | CA2 (0.50) | CA2CA1CA9CA12CA5A | |
| SCHEMBL9389558 | 0.81 | CA2 (0.51) | CA2CA1CA9SMN1; SMN2CA12 | |
| SCHEMBL24668639 | 0.81 | CA2 (0.51) | CA2CA1CA9CA12CA5A | |
| SCHEMBL9389553 | 0.80 | CA2 (0.53) | CA2CA1CA9CA12CA5A | |
| SCHEMBL9389605 | 0.80 | CA2 (0.53) | CA2CA1CA9CA12CA5A | |
| SCHEMBL9423584 | 0.71 | CA2 (0.37) | LOXLOXL2CA2CA1CA9 | |
| SCHEMBL2007145 | 0.70 | CA2 (0.39) | LOXLOXL2CA2CA1CA9 | |
| SCHEMBL24670395 | 0.69 | CA2 (0.42) | PDPK1CA2 | |
| SCHEMBL25208792 | 0.67 | CA2 (0.46) | CA2CA1CA9CA3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |