Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389553 | 1.00 | CA2 (0.53) | CA2CA12CA1CA4CA6 | |
| SCHEMBL24668639 | 0.98 | CA2 (0.51) | CA2CA12CA1CA4CA6 | |
| SCHEMBL24668662 | 0.93 | CA2 (0.50) | CA2CA12CA1CA4CA6 | |
| SCHEMBL9393144 | 0.84 | CA2 (0.50) | CA2CA12CA1CA5ACA7 | |
| SCHEMBL9389558 | 0.82 | CA2 (0.51) | CA2CA12CA1CA5ACA7 | |
| SCHEMBL24668632 | 0.82 | CA2 (0.33) | CA2CA12CA1CA4CA6 | |
| SCHEMBL24668657 | 0.80 | LOX (0.34) | CA2CA12CA1CA4CA6 | |
| SCHEMBL10340958 | 0.69 | CA2 (0.59) | CA2 | |
| SCHEMBL9423584 | 0.69 | CA2 (0.37) | CA2CA12CA1CA7CA9 | |
| SCHEMBL7600298 | 0.68 | LTB4R (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994005651-A1 | 5-SUBSTITUTED 3-THIOPHENE SULFONAMIDES AS ANTIGLAUCOMA AGENTS | ALLERGAN, INC. (US) | 1994-03-17 | — | — | WO | disclosed |