Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467414 | 0.89 | MET (0.49) | MET | |
| SCHEMBL2464380 | 0.87 | MET (0.63) | MET | |
| SCHEMBL2468137 | 0.86 | MET (0.53) | MET | |
| SCHEMBL2467459 | 0.85 | MET (0.53) | MET | |
| SCHEMBL2468334 | 0.85 | MET (0.63) | MET | |
| SCHEMBL2471696 | 0.85 | MET (0.51) | METPTGDR2CHRNE | |
| SCHEMBL2467270 | 0.83 | MET (0.53) | MET | |
| SCHEMBL2470648 | 0.82 | MET (0.45) | MET | |
| SCHEMBL2468886 | 0.81 | MET (0.50) | METPTGDR2 | |
| SCHEMBL2672462 | 0.81 | MET (0.63) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173653-B2 | Pyridiazinone derivatives for the treatment of tumours | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-08 | — | — | US | claimed |
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | claimed |