Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.61 |
| ▸ | MELK | Q14680 | 4/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803671 | 1.00 | SLC2A1 (0.61) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL30182258 | 0.99 | SLC2A1 (0.60) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL24891957 | 0.99 | SLC2A1 (0.60) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL29803659 | 0.94 | SLC2A1 (0.70) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL29803664 | 0.87 | SLC2A1 (0.47) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL24670573 | 0.86 | MAPKAPK2 (0.59) | SLC2A1MELKNAMPTMAPKAPK2 | |
| SCHEMBL29803392 | 0.85 | MELK (0.56) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL29803274 | 0.82 | ITGB3 (0.49) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL29803784 | 0.82 | SLC2A1 (0.49) | SLC2A1MELKF2PLGPLAU | |
| SCHEMBL29803480 | 0.82 | SLC2A1 (0.54) | SLC2A1MELKF2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |