Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669800 | 0.84 | RAB9A (0.51) | FPR2KMT2ANPC1RAB9ALMNA | |
| SCHEMBL24671090 | 0.81 | KMT2A (0.56) | FPR2KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4293848 | 0.79 | NPC1 (0.52) | FPR2KMT2ANPC1RAB9AHSD17B10 | |
| SCHEMBL29757930 | 0.78 | NPC1 (0.51) | FPR2KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4287692 | 0.75 | KMT2A (0.60) | KMT2ANPC1RAB9ALMNAMAPT | |
| SCHEMBL22773928 | 0.75 | KMT2A (0.53) | FPR2KMT2ANPC1RAB9ALMNA | |
| SCHEMBL1949535 | 0.73 | HSD17B10 (0.69) | KMT2ARAB9AHSD17B10LMNAALDH1A1 | |
| SCHEMBL13373362 | 0.72 | HSD17B10 (0.51) | KMT2ANPC1RAB9AHSD17B10LMNA | |
| SCHEMBL13373479 | 0.72 | HSD17B10 (0.51) | KMT2ANPC1RAB9AHSD17B10LMNA | |
| SCHEMBL4285419 | 0.72 | NPC1 (0.69) | KMT2ANPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |