Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803701 | 1.00 | MAPT (0.65) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL31642632 | 0.89 | MAPT (0.72) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL24669372 | 0.84 | RAB9A (0.56) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL24670312 | 0.84 | NPC1 (0.52) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL29803705 | 0.84 | NPC1 (0.52) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL24669490 | 0.82 | MAPT (0.48) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL29803528 | 0.82 | MAPT (0.48) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL3440627 | 0.82 | ALDH1A1 (0.59) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL30051993 | 0.82 | MAPT (0.71) | MAPTALDH1A1NPC1RAB9ADHODH | |
| SCHEMBL27007635 | 0.82 | NPC1 (0.62) | MAPTALDH1A1NPC1RAB9ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |