Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 7/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536591 | 0.82 | PDE3B (0.52) | PDE3BPDE3AHTR2CALOX5APFEN1 | |
| SCHEMBL27629619 | 0.82 | PDE3B (0.49) | PDE3BPDE3AHTR2CALOX5APFEN1 | |
| SCHEMBL24670558 | 0.80 | HTR6 (0.46) | HTR2CALOX5APFEN1HTR6SIGMAR1 | |
| SCHEMBL14320492 | 0.80 | HTR2C (0.46) | HTR2CHTR6SIGMAR1HTR1AHTR7 | |
| SCHEMBL12139643 | 0.80 | HTR2C (0.50) | PDE3BPDE3AHTR2CALOX5APFEN1 | |
| SCHEMBL12142090 | 0.79 | PDE3B (0.52) | PDE3BPDE3AHTR2CALOX5APFEN1 | |
| SCHEMBL3326760 | 0.78 | HTR2C (0.56) | PDE3BPDE3AHTR2CHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4589212 | 0.78 | HTR2C (0.56) | PDE3BPDE3AHTR2CHTR6SIGMAR1 | |
| SCHEMBL24670969 | 0.77 | HTR2C (0.51) | HTR2CHTR6SIGMAR1HTR1AHTR7 | |
| SCHEMBL519626 | 0.77 | HTR6 (0.50) | POLBPDE3BPDE3AHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |