Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 7/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | QDPR | P09417 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29882492 | 0.83 | HTR6 (0.50) | HTR6HTR2CSIGMAR1QDPRDRD2 | |
| SCHEMBL1513540 | 0.83 | HTR6 (0.50) | HTR6HTR2CSIGMAR1QDPRDRD2 | |
| SCHEMBL19212311 | 0.82 | HTR2C (0.41) | HTR6HTR2CALOX5APFEN1SIGMAR1 | |
| SCHEMBL26938532 | 0.81 | DRD2 (0.49) | HTR6HTR2CALOX5APFEN1SIGMAR1 | |
| SCHEMBL23291524 | 0.81 | HTR2C (0.60) | HTR6HTR2CALOX5APFEN1SIGMAR1 | |
| SCHEMBL24670969 | 0.81 | HTR2C (0.51) | HTR6HTR2CSIGMAR1QDPRKDM4E | |
| SCHEMBL31223007 | 0.81 | HTR2C (0.60) | HTR6HTR2CALOX5APFEN1SIGMAR1 | |
| SCHEMBL14320492 | 0.81 | HTR2C (0.46) | HTR6HTR2CSIGMAR1QDPRKDM4E | |
| SCHEMBL24670167 | 0.80 | GLA (0.54) | HTR6HTR2CALOX5APFEN1SIGMAR1 | |
| SCHEMBL30928085 | 0.78 | HTR6 (0.59) | HTR6HTR2CALOX5APFEN1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| CN-1072222-C | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | UPJOHN CO (US) | 2001-10-03 | — | — | CN | disclosed |
| CN-1197457-A | Phenyloxazolidinones having a C-C bond to a 4-8 membered heterocyclic ring | UPJOHN CO (US) | 1998-10-28 | — | — | CN | disclosed |