Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670776 | 1.00 | HTR1D (0.38) | HTR1DMCHR1NAMPTHTR1BHTR2A | |
| SCHEMBL24670220 | 0.97 | NAMPT (0.38) | HTR1DNAMPTHTR1BHTR2ATMPRSS2 | |
| SCHEMBL29803531 | 0.97 | NAMPT (0.38) | HTR1DNAMPTHTR1BHTR2ATMPRSS2 | |
| SCHEMBL29803328 | 0.94 | NAMPT (0.40) | HTR1DNAMPTHTR1BHTR2ATMPRSS2 | |
| SCHEMBL24669444 | 0.92 | NAMPT (0.42) | HTR1DMCHR1NAMPTTMPRSS2SLC6A4 | |
| SCHEMBL24669435 | 0.92 | NAMPT (0.42) | HTR1DMCHR1NAMPTTMPRSS2SLC6A4 | |
| SCHEMBL24670867 | 0.92 | MAPT (0.39) | NAMPTTMPRSS2MAPTROCK2KMT2A | |
| SCHEMBL24670860 | 0.92 | MAPT (0.39) | NAMPTTMPRSS2MAPTROCK2KMT2A | |
| SCHEMBL24671182 | 0.92 | NAMPT (0.38) | NAMPTTMPRSS2MAPTKMT2ASCN9A | |
| SCHEMBL29803596 | 0.92 | NAMPT (0.38) | NAMPTTMPRSS2MAPTKMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |