Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670860 | 1.00 | MAPT (0.39) | MAPTSMN1; SMN2TP53THRBMAOB | |
| SCHEMBL29803748 | 0.95 | NAMPT (0.40) | MAPTSMN1; SMN2TP53THRBTRPV1 | |
| SCHEMBL24670832 | 0.94 | MAPT (0.37) | MAPTSMN1; SMN2TP53THRBMAOB | |
| SCHEMBL24670776 | 0.92 | HTR1D (0.38) | MAPTSMN1; SMN2NAMPTROCK2TMPRSS2 | |
| SCHEMBL29803651 | 0.92 | TRPV1 (0.39) | MAPTSMN1; SMN2TP53TRPV1NAMPT | |
| SCHEMBL24670811 | 0.92 | TRPV1 (0.39) | MAPTSMN1; SMN2TP53TRPV1NAMPT | |
| SCHEMBL24670179 | 0.92 | HTR1D (0.38) | MAPTSMN1; SMN2NAMPTROCK2TMPRSS2 | |
| SCHEMBL24669435 | 0.92 | NAMPT (0.42) | NAMPTTMPRSS2ABCB1 | |
| SCHEMBL24669444 | 0.92 | NAMPT (0.42) | NAMPTTMPRSS2ABCB1 | |
| SCHEMBL24671182 | 0.91 | NAMPT (0.38) | MAPTSMN1; SMN2TP53THRBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |