Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803596 | 1.00 | NAMPT (0.38) | NAMPTNPC1KCNQ3KCNQ2CCNT1 | |
| SCHEMBL29803193 | 0.95 | NAMPT (0.40) | NAMPTNPC1CDK9SCN9ATP53 | |
| SCHEMBL29803771 | 0.93 | TRPV1 (0.39) | NAMPTSCN9ATRPV1 | |
| SCHEMBL24670267 | 0.93 | TRPV1 (0.39) | NAMPTSCN9ATRPV1 | |
| SCHEMBL24671542 | 0.93 | CDK9 (0.36) | NAMPTNPC1CCNT1CDK9MAPT | |
| SCHEMBL24670237 | 0.93 | CDK9 (0.36) | NAMPTNPC1CCNT1CDK9MAPT | |
| SCHEMBL24671294 | 0.93 | MAPT (0.37) | NAMPTNPC1TP53MAPTTHRB | |
| SCHEMBL24671296 | 0.93 | MAPT (0.37) | NAMPTNPC1TP53MAPTTHRB | |
| SCHEMBL24669443 | 0.93 | KCNQ3 (0.38) | NAMPTNPC1KCNQ3KCNQ2CCNT1 | |
| SCHEMBL24669449 | 0.93 | KCNQ3 (0.38) | NAMPTNPC1KCNQ3KCNQ2CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |