Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTR1D | P28221 | 3/20 | 0.54 |
| ▸ | HTR1B | P28222 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803724 | 1.00 | MAPT (0.72) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL29803640 | 0.89 | RAB9A (0.65) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL29803936 | 0.89 | MAPT (0.90) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL24670696 | 0.89 | RAB9A (0.65) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL24671107 | 0.89 | MAPT (0.90) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL24670851 | 0.82 | MAOB (0.59) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL29803287 | 0.82 | MAOB (0.59) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL30182470 | 0.82 | RAB9A (0.60) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL24670802 | 0.82 | MAPT (0.67) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL24670701 | 0.80 | TP53 (0.63) | MAPTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |