Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671107 | 0.85 | MAPT (0.90) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL29803936 | 0.85 | MAPT (0.90) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24670914 | 0.85 | HTR1D (0.65) | MAPTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL24671458 | 0.85 | ABCB1 (0.63) | MAPTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL29803730 | 0.84 | GRM4 (0.56) | MAPTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL24669380 | 0.84 | GRM4 (0.56) | MAPTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL24670265 | 0.83 | GRM4 (0.55) | MAPTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL24670737 | 0.82 | HTR1D (0.61) | MAPTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL29803389 | 0.82 | HTR1D (0.61) | MAPTGRM4NPC1RAB9AMEN1 | |
| SCHEMBL24670187 | 0.82 | MAPT (0.72) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |