Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 10/20 | 0.64 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29803685 | 0.93 | MAPKAPK2 (0.56) | MAPKAPK2IRAK4NAMPTPTPN1PTPN11 | |
| SCHEMBL24670344 | 0.91 | MAPKAPK2 (0.66) | MAPKAPK2IRAK4NAMPTPTPN1KLK7 | |
| SCHEMBL29803788 | 0.82 | MAPKAPK2 (0.54) | MAPKAPK2NAMPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL24669274 | 0.81 | MAPKAPK2 (0.59) | MAPKAPK2IRAK4PTPN1MAPTMAPK1 | |
| SCHEMBL24891832 | 0.77 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTCSF1R | |
| SCHEMBL24891696 | 0.77 | MAPKAPK2 (0.49) | MAPKAPK2NAMPT | |
| SCHEMBL29803401 | 0.77 | CCNT1 (0.45) | MAPKAPK2NAMPT | |
| Hydrochloric Acid SCHEMBL29803692 | 0.77 | CCNT1 (0.45) | MAPKAPK2NAMPT | |
| SCHEMBL24670454 | 0.77 | MAPKAPK2 (0.47) | MAPKAPK2NAMPTCSF1R | |
| SCHEMBL29803527 | 0.77 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTMAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |