Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | QDPR | P09417 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29803477 | 0.91 | MAPKAPK2 (0.48) | MAPKAPK2NAMPTULK1WNT3AHTR2C | |
| SCHEMBL24669231 | 0.88 | MAPKAPK2 (0.52) | MAPKAPK2NAMPTULK1WNT3AQDPR | |
| SCHEMBL29803788 | 0.83 | MAPKAPK2 (0.54) | MAPKAPK2NAMPTQDPR | |
| Trifluoroacetic Acid SCHEMBL29803754 | 0.81 | MAPKAPK2 (0.46) | MAPKAPK2NAMPTULK1QDPRSIGMAR1 | |
| SCHEMBL24670483 | 0.80 | ULK1 (0.41) | MAPKAPK2NAMPTULK1QDPRSIGMAR1 | |
| SCHEMBL29803527 | 0.80 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTWNT3AQDPRHTR2C | |
| SCHEMBL24670471 | 0.79 | SLC6A3 (0.42) | MAPKAPK2NAMPTWNT3A | |
| SCHEMBL24891696 | 0.78 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTWNT3AQDPRSIGMAR1 | |
| SCHEMBL24891832 | 0.78 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTWNT3AQDPRSIGMAR1 | |
| SCHEMBL24670465 | 0.77 | MAPKAPK2 (0.64) | MAPKAPK2NAMPTCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |