Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | QDPR | P09417 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29803510 | 0.92 | MAPKAPK2 (0.53) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| SCHEMBL24669213 | 0.88 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTCSF1R | |
| SCHEMBL24669887 | 0.87 | MAPKAPK2 (0.48) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| SCHEMBL24670537 | 0.85 | MAPKAPK2 (0.45) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| SCHEMBL24671307 | 0.84 | WNT3A (0.54) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL29803272 | 0.82 | MAPKAPK2 (0.49) | MAPKAPK2NAMPTCSF1R | |
| Trifluoroacetic Acid SCHEMBL29803620 | 0.82 | MAPKAPK2 (0.43) | MAPKAPK2NAMPTHTR2CSIGMAR1CSF1R | |
| SCHEMBL24670573 | 0.80 | MAPKAPK2 (0.59) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL29803316 | 0.80 | MAPKAPK2 (0.41) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL29803488 | 0.78 | WNT3A (0.49) | MAPKAPK2NAMPTQDPRHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |