Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385110 | 0.83 | GRM4 (0.48) | GRM4ABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL15476219 | 0.82 | GRM4 (0.47) | GRM4ABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL31276213 | 0.82 | GRM4 (0.47) | GRM4ABCG2ABCB1ABCC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8202141 | 0.80 | GRM4 (0.46) | GRM4ABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL27261405 | 0.79 | ALDH1A1 (0.51) | GRM4ABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL12555538 | 0.77 | GRM4 (0.47) | GRM4ABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL3177974 | 0.77 | GRM4 (0.43) | GRM4ABCG2ABCB1ABCC1ALDH1A1 | |
| SCHEMBL526859 | 0.76 | CYP17A1 (0.55) | GRM4ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL879728 | 0.76 | GRM4 (0.59) | GRM4ALDH1A1MAPTSTAT1SMN1; SMN2 | |
| SCHEMBL15972268 | 0.76 | GRM4 (0.59) | GRM4ABCG2ABCB1ABCC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |