Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.38 |
| ▸ | CDK9 | P50750 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802833 | 0.95 | TMPRSS2 (0.46) | TMPRSS2CCNT1CDK9MAPTTRPV1 | |
| SCHEMBL24670857 | 0.89 | TMPRSS2 (0.45) | TMPRSS2CCNT1CDK9MAPTTRPV1 | |
| SCHEMBL29803204 | 0.85 | TMPRSS2 (0.52) | TMPRSS2MAPTTRPV1POLB | |
| SCHEMBL24671270 | 0.85 | TMPRSS2 (0.52) | TMPRSS2MAPTTRPV1POLB | |
| SCHEMBL29803214 | 0.84 | TMPRSS2 (0.52) | TMPRSS2MAPTTRPV1 | |
| SCHEMBL24670599 | 0.84 | TRPV1 (0.45) | TMPRSS2MAPTTRPV1 | |
| SCHEMBL24669468 | 0.83 | TMPRSS2 (0.52) | TMPRSS2MAPTTRPV1POLB | |
| SCHEMBL24669503 | 0.81 | PDK4 (0.46) | CCNT1CDK9 | |
| SCHEMBL24669447 | 0.81 | TMPRSS2 (0.48) | TMPRSS2MAPT | |
| SCHEMBL29803358 | 0.80 | TMPRSS2 (0.47) | TMPRSS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |