Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.45 |
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802958 | 0.94 | TRPV1 (0.47) | TRPV1TMPRSS2 | |
| SCHEMBL24671240 | 0.91 | TMPRSS2 (0.46) | TRPV1TMPRSS2 | |
| SCHEMBL29802859 | 0.91 | TMPRSS2 (0.46) | TRPV1TMPRSS2 | |
| SCHEMBL29803214 | 0.86 | TMPRSS2 (0.52) | TRPV1TMPRSS2NPC1MAPTRAB9A | |
| SCHEMBL24669468 | 0.85 | TMPRSS2 (0.52) | TRPV1TMPRSS2MEN1NPC1MAPT | |
| SCHEMBL24670871 | 0.84 | TMPRSS2 (0.42) | TRPV1TMPRSS2MAPT | |
| SCHEMBL29803204 | 0.83 | TMPRSS2 (0.52) | TRPV1TMPRSS2MEN1NPC1MAPT | |
| SCHEMBL24671270 | 0.83 | TMPRSS2 (0.52) | TRPV1TMPRSS2MEN1NPC1MAPT | |
| SCHEMBL24669281 | 0.81 | WDR5 (0.48) | TRPV1 | |
| SCHEMBL29803609 | 0.81 | WDR5 (0.48) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |