Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 5/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803183 | 1.00 | NAMPT (0.36) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL24670898 | 1.00 | NAMPT (0.36) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL24670954 | 0.95 | NAMPT (0.36) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL29803260 | 0.95 | NAMPT (0.36) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL24670323 | 0.95 | NAMPT (0.36) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL29803536 | 0.90 | NAMPT (0.40) | NAMPTSOS1PRMT5WDR77CDK7 | |
| SCHEMBL29803446 | 0.88 | NAMPT (0.40) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL24671356 | 0.88 | NAMPT (0.40) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL24671289 | 0.88 | NAMPT (0.40) | NAMPTSOS1WDR5PRMT5WDR77 | |
| SCHEMBL24670839 | 0.87 | WDR5 (0.35) | NAMPTWDR5CDK9CCNT1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |