Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803679 | 0.91 | LMNA (0.50) | HTR1DHTR1BHTR2AMAPTLMNA | |
| SCHEMBL24670245 | 0.91 | LMNA (0.50) | HTR1DHTR1BHTR2AMAPTLMNA | |
| SCHEMBL24669461 | 0.86 | NAMPT (0.45) | MAPTSMN1; SMN2L3MBTL1TP53THRB | |
| SCHEMBL24670621 | 0.85 | CHRM1 (0.57) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL24669307 | 0.85 | LMNA (0.51) | HTR1DHTR1BHTR2AMAPTLMNA | |
| SCHEMBL24670886 | 0.84 | NPY2R (0.52) | HTR1DHTR1BHTR2AMAPTLMNA | |
| SCHEMBL9332403 | 0.80 | HTR1D (0.58) | HTR1DHTR1BHTR2AMAPTLMNA | |
| SCHEMBL24670647 | 0.80 | LMNA (0.53) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL27202624 | 0.79 | L3MBTL1 (0.56) | MAPTLMNAALDH1A1HPGDHTT | |
| SCHEMBL24670246 | 0.79 | NAMPT (0.47) | MAPTHTTL3MBTL1USP30F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |