Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 7/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669639 | 0.86 | NAMPT (0.45) | CCNT1CDK9NAMPT | |
| SCHEMBL29803037 | 0.85 | TMPRSS2 (0.41) | TMPRSS2BTKNAMPT | |
| SCHEMBL24671431 | 0.85 | NAMPT (0.48) | TMPRSS2CCNT1CDK9EGLN1NAMPT | |
| SCHEMBL24669447 | 0.82 | TMPRSS2 (0.48) | TMPRSS2NAMPT | |
| SCHEMBL29802865 | 0.82 | TMPRSS2 (0.43) | TMPRSS2CCNT1CDK9BTK | |
| SCHEMBL29803204 | 0.82 | TMPRSS2 (0.52) | TMPRSS2NAMPT | |
| SCHEMBL24671270 | 0.82 | TMPRSS2 (0.52) | TMPRSS2NAMPT | |
| SCHEMBL29803214 | 0.80 | TMPRSS2 (0.52) | TMPRSS2NAMPT | |
| SCHEMBL24669468 | 0.80 | TMPRSS2 (0.52) | TMPRSS2 | |
| SCHEMBL24669518 | 0.80 | TMPRSS2 (0.38) | TMPRSS2CCNT1CDK9BTKNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |