Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803275 | 0.88 | WNT3A (0.41) | NAMPTCCNT1CDK9F10 | |
| SCHEMBL24671395 | 0.88 | WNT3A (0.41) | NAMPTCCNT1CDK9F10 | |
| SCHEMBL24669518 | 0.87 | TMPRSS2 (0.38) | NAMPTCCNT1CDK9TMPRSS2TRPV1 | |
| SCHEMBL24669447 | 0.87 | TMPRSS2 (0.48) | NAMPTLMNAMAPTHTTNPSR1 | |
| SCHEMBL24670964 | 0.85 | TMPRSS2 (0.40) | NAMPTCCNT1CDK9TMPRSS2EGLN1 | |
| SCHEMBL24670963 | 0.85 | CCNT1 (0.40) | MAPTHTTCCNT1CDK9TMPRSS2 | |
| SCHEMBL24670318 | 0.84 | TMPRSS2 (0.38) | NAMPTLMNAMAPTHTTNPSR1 | |
| SCHEMBL29803476 | 0.84 | NAMPT (0.49) | NAMPTCCNT1CDK9 | |
| SCHEMBL29803214 | 0.83 | TMPRSS2 (0.52) | NAMPTLMNAMAPTTMPRSS2TRPV1 | |
| SCHEMBL24670961 | 0.82 | TMPRSS2 (0.41) | CCNT1CDK9TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |