Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898927 | 0.86 | NAMPT (0.58) | MAPTTDP1KDM4EGLAGAA | |
| SCHEMBL29803635 | 0.85 | NR1H4 (0.43) | MAPTTDP1KDM4EGLAGAA | |
| SCHEMBL24670292 | 0.81 | SMN1; SMN2 (0.58) | MAPTTDP1NAMPTNPSR1HDAC1 | |
| SCHEMBL5726306 | 0.80 | HTT (0.52) | MAPTTDP1GAACA1CA2 | |
| SCHEMBL22822779 | 0.78 | MEN1 (0.62) | MAPTKDM4EGAAPAX8LMNA | |
| SCHEMBL23899245 | 0.77 | NAMPT (0.72) | MAPTTDP1NAMPTNPSR1XBP1 | |
| SCHEMBL24671047 | 0.76 | RAB9A (0.56) | MAPTTDP1KDM4ENAMPTNPSR1 | |
| SCHEMBL23899104 | 0.76 | HDAC1 (0.56) | MAPTTDP1GAANAMPTCA1 | |
| SCHEMBL24670461 | 0.76 | PTPN11 (0.53) | MAPTTDP1KDM4EGLAGAA | |
| SCHEMBL6819042 | 0.76 | RAB9A (0.56) | MAPTKDM4EGAANAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |