Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670292 | 0.88 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL6814592 | 0.86 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL24669430 | 0.82 | NAMPT (0.55) | LMNAMAPTNAMPTKMT2AMEN1 | |
| SCHEMBL2873843 | 0.80 | NAMPT (0.64) | RAB9ANPC1NAMPTKMT2AMEN1 | |
| SCHEMBL19889037 | 0.79 | NAMPT (0.60) | RAB9ANPC1LMNANAMPTHPGD | |
| SCHEMBL23898927 | 0.79 | NAMPT (0.58) | L3MBTL1MAPTNAMPTNPSR1MAPK1 | |
| SCHEMBL16193024 | 0.79 | NAMPT (0.62) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24671051 | 0.79 | NAMPT (0.52) | ALDH1A1LMNANAMPT | |
| SCHEMBL24667825 | 0.79 | NAMPT (0.56) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1065312 | 0.78 | CA2 (0.55) | RAB9ANPC1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |