Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.49 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.42 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670487 | 0.87 | NAMPT (0.61) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL29803615 | 0.85 | NAMPT (0.44) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24670527 | 0.85 | NAMPT (0.44) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24669270 | 0.85 | NAMPT (0.44) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL22165464 | 0.84 | NAMPT (0.56) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24670528 | 0.83 | NAMPT (0.46) | NAMPT | |
| SCHEMBL24669665 | 0.81 | NAMPT (0.48) | NAMPTCDK7CDK13CDK12WNT3A | |
| Trifluoroacetic Acid SCHEMBL29803709 | 0.80 | NAMPT (0.43) | NAMPT | |
| SCHEMBL29803476 | 0.80 | NAMPT (0.49) | NAMPTCDK7CDK13CDK12WNT3A | |
| SCHEMBL24669237 | 0.80 | NAMPT (0.50) | NAMPTCDK7CDK13CDK12WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |